PUBLICATION LIST
Journal Articles
- Nao SC, Huang LS, Chan D, Wang XL, Li GD, Wu J, Wong CY*, Wang WH* and Leung CH (Corresponding author)* . (2024) Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate cancer using a time-resolved oligonucleotide-based drug screening platform. Bioorg Chem
- Nao SC, Kong LT, Chan D, Liu JH, Huang LS, Wu L, Wu J, Wong CY*, Wang WH* and Leung CH (Corresponding author)*.(2023) Covalent inhibition of epidermal growth factor receptor using a long-lived iridium (III)-afatinib probe. Int J Biol Macromol
- Jing SZ, Wu XL, Niu D, Wang J*, Wang WH* and Leung CH (Corresponding author)*.(2023) Recent advances in organometallic NIR iridium(III) complexes for detection and therapy. Molecules
- Wang L, Wang XL, Chen F, Song YQ, Nao SC, Chan D, Wong CY, Wang WH* and Leung CH (Corresponding author)*. (2023) A glycyrrhetinic acid-iridium(III) conjugate as a theranostic NIR probe for hepatocellular carcinoma with mitochondrial-targeting ability. Eur J Med Chem
- Wang L, Liu JQ, Chen F, Li GD, Wang J, Chan D, Wong CY, Wang WH* and Leung CH (Corresponding author)*. (2023)A switch-on affinity-based iridium(III) conjugate probe for imaging mitochondrial glutathione S-transferase in breast cancer cells. Bioconjug Chem 34, 1727-1737.
- Wang Y, Yin L, Qu GX, Leung CH, Han L, and Lu LH* (2023) Highly Active Single-Atom Nanozymes with High-Loading Iridium for Sensitive Detection of Pesticides. Anal. Chem 95, 11960-11968.
- Yang XF, Nao SC, Lin CK, Kong LT, Wang J, Ko NC, Liu JB, Ma DL, Leung CH (Corresponding author)* and Wang WH* (2023) A cell-impermeable luminogenic probe for near-infrared imaging of prostate-specific membrane antigen in prostate cancer microenvironments. Eur J Med Chem 259, 5, 115658.
- Song YQ, Li GD, Niu D, Chen F, Jing SZ, Vincent Wong KW, Wang WH* and Leung CH (Corresponding author)*. (2023) A robust luminescent assay for screening alkyladenine DNA glycosylase inhibitors to overcome DNA repair and temozolomide drug resistance. J Pharm Anal 13, 5, 514-522
- Wang ZK, Wang WH*, and Leung CH (Corresponding author)*. (2023) Strategies for Developing Cancer Theranostics Approaches. Recent Pat Anti-canc, (In press)
- Wang WH*, Liu JH, Kong LT, Wang L, Niu D, Wang J*, and Leung CH (Corresponding author)*. (2023) Synthesis and luminescence monitoring of iridium(III) complex-functionalized gold nanoparticles and their application for determination of gold(III) ions. Mikrochim Acta 190, 171.
- Li GD, Huang Q, Wong KW, Wang WH* and Leung CH (Corresponding author)*. (2023) Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment. Genes Dis 10, 6, 2260-2262.
- Song YQ, Yang GJ*, Ma DL, Wang WH* and Leung CH (Corresponding author)*. (2023) The role and prospect of lysine-specific demethylases in cancer chemoresistance. Med Res Rev 43, 5, 1438-1469.
- Liu JQ, Wang XL, Wang J*, Leung CH (Corresponding author)* and Wang WH*.(2023) Imaging mitochondrial palladium species in living cells with a NIR iridium(III) complex. Spectrochim. Acta A Mol. Biomol. Spectrosc 288, 122188.
- Song YQ, Wu KJ, Zhang ZM, Liu TM, Ko NC, Zhu WG, Ma DL*, Wang WH* and Leung CH (Corresponding author)*. (2023) Development of a sensitive luminescent probe to uncover new BRD4 inhibitors in living cells. Chem Eng J 463, 142356
- Wu J, Wang WH*, and Leung CH (Corresponding author)*. (2023) Computational Strategies for PROTAC Drug Discovery. Acta Materia Medica 2, 1, 42-54.
- Cheng SS, Kuang Y, Li GD, Wu J, Ko NC, Wang WH, Ma DL*, Ye M* and Leung CH (Corresponding author)*. (2022) Dehydroeburicoic Acid, a Dual Inhibitor against Oxidative Stress in Alcoholic Liver Disease. Pharmaceutics 16, 14.
- Lin CK, Wang XL, Nao SC, Wang J, Liu JB*, Ma DL, Zhu WG, Leung CH (Corresponding author)* and Wang WH*. (2022) A labile iridium(III) complex-based luminogenic probe for the ratiometric detection of dithiocarbamate compounds in living system. Sens. Actuators B Chem 378, 133133.
- Li GD, Ko CN, Wang ZK, Chen F, Wang WH*, Ma DL* and Leung CH (Corresponding author)*. (2022) Interference reduction isothermal nucleic acid amplification strategy for COVID-19 variant detection. Sens. Actuators B Chem 377, 133006.
- Wang WH*, Liu JH, Nao SC, Ma DL, Wang J*, and Leung CH (Corresponding author) *.(2022) Affinity-based luminescent iridium(III) complexes for the detection of disease-related proteins. Inorganics 10, 178.
- Zhong HJ, Wang WH, Zhou W, Liang JX, Cheng YC*, Ma DL* and Leung CH (Corresponding author) *.(2022) Development of an orally bioavailable selective inhibitor of the menin-MLL. Genes Dis 10(5), 1735-1738.
- Lin CK, Wang J, Yang K, Liu JB*, Ma DL, Leung CH (Corresponding author) * and Wang WH*.(2022) Development of a NIR iridium(III) complex for self-calibrated and luminogenic detection of boron trifluoride. Spectrochim Acta - A: Mol Biomol Spectrosc 282, 121658.
- Wang Y, Zhu FY, Yin L, Qu GX, Ma DL* and Leung CH (Corresponding author) *, Lu LH*.(2022) Ratiometric fluorescent detection of pesticide based on split aptamer and magnetic separation. Sensor Actuat B-Chem 367, 132045.
- Zhu JZ, Chen C, Dong J, Cheng SS, Li GD, Wang CM, Ouyang DF, Leung CH and Lin LG*. (2022) Artificial intelligence-aided discovery of prolyl hydroxylase 2 inhibitors to stabilize hypoxia inducible factor-1α and promote angiogenesis. Chinese Chem Lett 34, 107514.
- Li GD, Li D, Wu C, Li SN, Chen F, Li P, Ko CN, Wang WH, Li MY, Lin LG*, Ma DL* and Leung CH (Corresponding author)*. (2022) Homocysteine-targeting compounds as a new treatment strategy for diabetic wounds via histone methyltransferase SET7/9 inhibition. Exp Mol Med 54,988–998.
- Ning C, Jiao YH, Wang JQ, Li WW, Zhou JQ, Lee YC, Ma DL, Leung CH, Zhu RG* and Wang HM*. (2022) Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances. Food SciI Hum Well 11, 5, 1121-1133.
- Cheng SS, Yang GJ, Wang WH, Song YQ, Ko CN, Han QB, Ma DL* and Leung CH (Corresponding author)*. (2022) Identification of a cytisine-based EED-EZH2 protein-protein interaction inhibitor against metastasis in triple-negative breast cancer cells. Acta Materia Medica 1, 2, 197-211.
- Zhang H, Sun M, Wang Y, Yin L, Ma DL*, Leung CH (Corresponding author)* and Lu LH*. (2022) A time-resolved ratiometric luminescent anthrax biomarker nanosensor based on an Ir(III) complex-doped coordination polymer network. J Mater Chem B 10, 1853-1857.
- Lin YY, Chen CY, Ma DL, Leung CH, Chang CY and Wang HM*. (2022) Cell-derived artificial nanovesicle as a drug delivery system for malignant melanoma treatment. Biomed. Pharmacother 147, 112586.
- Chen F, Li GD, Wu C, Wang L, Ko CN, Ma DL* and Leung CH (Corresponding author)*. (2022) An interference reduction biosensing strategy for highly sensitive microRNA detection. Anal Chem 94, 10, 4513–452.
- Chen F, Li GD, Wu C, Wang WH, Ma DL* and Leung CH (Corresponding author)*. (2021) A Rapid and Label-Free DNA-based Interference Reduction Nucleic Acid Amplification Strategy for Viral RNA Detection. Biosens Bioelectron 198, 113829.
- Yang GJ, Wu J, Leung CH (Corresponding author)*, Ma DL* and Chen J*. (2021) A Review on the Emerging Roles of Pyruvate Kinase M2 in Anti-leukemia Therapy. Int J Biol Macromol 193, 1499-1506.
- Cheng SS, Qu YQ, Wu J, Yang GJ, Liu H, Wang WH, Huang Q, Chen F, Li GD, Wong CY, Vincent Wong KW*, Ma DL*, and Leung CH (Corresponding author)*. (2021) Inhibition of the CDK9‒cyclin T1 protein‒protein interaction as a new approach against triple-negative breast cancer. Acta Pharm Sin B 12, 1390-1405.
- Yang GJ, Wu J, Miao L, Zhu MH, Zhou QJ, Lu XJ, Lu JF, Leung CH (Corresponding author)*, Ma DL*, and Chen J*. (2021) Pharmacological inhibition of KDM5A for cancer treatment. Eur J Med Chem 226, 113855.
- Li GD, Liu H, Feng RB, Kand TS, Wang WH, Ko CN, Wong CY, Ye M, Ma DL*, Wan JB* and Leung CH (Corresponding author)*. (2021) A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury. Redox Biol 48, 102129.
- Yang GJ, Song YQ, Wang WH, Han QB*, Ma DL* and Leung CH (Corresponding author)*. (2021) An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells. Biooge Chem 114, 105158.
- Wu KJ, Wu C, Fang M, Ding BB, Liu PP, Zhou MX, Gong ZY*, Ma DL* and Leung CH (Corresponding author)*. (2021) Application of metal–organic framework for the adsorption and detection of food contamination. Trends Analyt Chem 114, 116384.
- Bao WR, Zhang QW, Zheng HM, Li LF, Liu M, Cheng HY, Wong TL, Zhang G, Lu AP, Bian ZX, Ma DL*, Leung CH (Corresponding author)* and Han QB*. (2021) Radix Astragali polysaccharide RAP directly protects hematopoietic stem cells from chemotherapy-induced myelosuppression by increasing FOS expression. Int J Biol Macromol 183,1715.
- Cheng SS, Yang GJ, Wang WH, Ma DL* and Leung CH (Corresponding author)*. (2021) Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein-protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells. Genes Dis 9, 6, 1674-1688.
- Song YQ, Wu C, Wu KJ, Han QB, Miao XM, Ma DL* and Leung CH (Corresponding author)*. (2021) Ubiquitination regulators discovered by virtual screening for the treatment of cancer. Front Cell Dev Biol 9, 665646.
- Li GD, Ko CN, Li D, Yang C, Wang WH, Yang GJ, Di Primo C, Wong KW, Xiang YZ, Lin LG*, Ma DL* and Leung CH (Corresponding author)*. (2021) A small molecule HIF-1α stabilizer that accelerates diabetic wound healing. Nat Commun 12, 1, 3363.
- Ning C, Jiao YH, Wang JQ, Li WW, Zhou JQ, Lee YC, Ma DL, Leung CH, Zhu RG, Wang HM*. (2021) Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances. Food Sci Hum Wellness 11, 5, 1121-1133.
- Li GD, Wu C, Ma DL*, and Leung CH (Corresponding author)*. (2021) Drug screening strategies using metal-based luminescent probes. Trends Analyt Chem 139, 116270.
- Yang GJ, Zhu MH, Lu XJ, Liu YJ, Lu JF, Leung CH (Corresponding author)*, Ma DL* and Chen J*. (2021) The emerging role of KDM5A in human cancer. J Hematol Oncol 14, 30.
- Wu KJ, Wu C, Chen F, Cheng SS, Ma DL* and Leung CH (Corresponding author)*. (2020) A time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells. ACS Sens 6, 166.
- Wu KJ, Ho SH, Wu C, Wang HMD*, Ma DL* and Leung CH (Corresponding author)*. (2020) Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma. J Cell Mol Med 25, 1972.
- Wu C, Wu KJ, Liu JB, Wang WH, Leung CH (Corresponding author)* and Ma DL*. (2020) Structure-guided discovery of a luminescent theranostic toolkit for living cancer cells and the imaging behavior effect. Chem Sci 11, 11404. Front cover
- Yang GJ, Wang WH, Lei PM, Leung CH (Corresponding author)* and Ma DL*. (2020) A 7-Methoxybicoumarin Derivative Selectively Inhibits BRD4 BD2 for Anti-Melanoma Therapy. Int J Biol Macromol 164, 3204.
- Nao SC, Wu KJ, Wang WH, Leung CH (Corresponding author)* and Ma DL*. (2020) Recent progress and development of G-quadruplex-based luminescent assays for ochratoxin A detection. Front Chem 8, 767.
- Wang WH, Wu KJ, Vellaisamy K, Leung CH (Corresponding author)* and Ma DL*. (2020) Peptide‐conjugated long‐lived theranostic imaging toolbox for targeting GRPr in cancer and immune cells. Angew Chem Int Ed 59,17897. Inside cover
- Wu KJ, Wang WH, Wang HM, Leung CH (Corresponding author)* and Ma DL*. (2020) Interfering with S100B-effector protein interactions for cancer therapy. Drug Discov. Today 25, 9, 1754.
- Chou HY, Ma DL, Leung CH, Chiu CC, Hour TZ* and Wang HM*, (2020) Purified astaxanthin from Haematococcus pluvialis promotes tissue regeneration by reducing oxidative stress and the secretion of collagen in vitro and in vivo. Oxid Med Cell Longev 2020.
- Wang WH, Yung TL, Cheng SS, Chen F, Liu JB*,Leung CH (Corresponding author)*, Ma DL*. (2020) A long-lived luminogenic iridium(III) complex for acetylacetone detection in environmental samples. Sensor Actuat B Chem 321, 128486.
- Ko CN, Cheng SS, Leung CH (Corresponding author)*, Ma DL*. (2020) A long-lived phosphorescence amplification system intergrated with graphene oxide and a stable split G-quadruplex protector as an isothermal “off-on” bio sensor for the HBV gene. ACS Appl Bio Mater 3, 7, 4556.
- Chen F, Li GD, Liu H, Leung CH (Corresponding author)*, Ma DL*. (2020) G-quadruplex-based detection of glyphosate in complex biological systems by a time-resolved luminescent assay. Sensor Actuat B Chem 320, 128393.
- Wu KJ, Ho HS, Dong JY, Fu L, Wang SP, Liu H, Wu C, Leung CH (Corresponding author)*, Wang HM*, Ma DL*. (2020) An aliphatic group-tethered iridium complex as a theranostic agent against malignant melanoma metastasis. ACS Appl Bio Mater 3, 4, 2017.
- Li LF, Wong TL, Zhang JX, Zhou LS, Bai SP, Fung HY, Cheng HY, Zhang QW, Zheng HM, Bao WR, Ma DL, Leung CH, Zhang G, Bian ZX, Lyu AP, Han QB* (2020) An oligosaccharide-marker approach to quantify specific polysaccharides in herbal formula by LC-qTOF-MS: Danggui Buxue Tang, a case study. J. Pharm Biomed Anal 185, 113235.
- Ma DL*, Wu C, Li GD, Yung TL, Leung CH (Corresponding author)* (2020) Transition metal complexes as imaging or therapeutic agents for neurodegenerative diseases. J Mater Chem 8, 22, 4715.
- Cheng SS, Yang GJ, Wang WH, Leung CH (Corresponding author)*, Ma DL*. (2019) The design and development of covalent protein-protein interaction inhibitors for cancer treatment. J Hematol Oncol 13, 1.
- Li B, Kuang Y, Zhang M, He JB, Xu LL, Leung CH, Ma DL, Lo JY, Qiao X* and Ye M*. (2020) Cytotoxic triterpenoids from: Antrodia camphorata as sensitizers of paclitaxel. Organic Chemistry Frontiers 7, 5, 768.
- Li GD, Stuart AH, Liu H, Kang TS, Nao SC, Zhao YC, Wu C, Jin JW, Zhang JT, Leung CH (Corresponding author)*, Chan PHC*, Ma DL*. (2019) A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer. Chem Sci 11,1750. Front cover
- Li D, Liu QY, Lu XQ, Li ZQ, Wang CM, Leung CH, Wang YT, Peng C*, Lin LG*. (2019) α-Mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders in mice. Aging 11(23), 11084.
- Wu KJ, Lei PM, Liu H, Wu C, Leung CH (Corresponding author)*, Ma DL*. (2019) Mimicking strategy for protein-protein interaction inhibitor discovery by virtual screening. Molecules 24, 24, 4428.
- Ma DL*, Wu C, Liu H, Wu KJ, Leung CH (Corresponding author)*. (2019) Luminescent approaches for the rapid detection of disease-related receptor proteins using transition metal-based probes. J Mater Chem B 8, 3249.
- Leung CH (Corresponding author)*, Zhang JT, Yang GJ, Liu H, Han QB, Ma DL*. (2019) Emerging screening approaches in the development of Nrf2-Keap1 protein-protein Interaction inhibitors. Int J Mol Sci 20, 18, 4445.
- Liu JB, Wu C, Chen F, Leung CH, Ma DL*. (2019) A simple iridium(III) dimer as a switch-on luminescent chemosensor for carbon disulfide detection in water samples. Anal Chim Acta 1083, 166.
- Yang GJ, Hao L, Ma DL*, Leung CH (Corresponding author)*. (2019) Rebalancing metal dyshomeostasis for Alzheimer's disease therapy. J Biol Inorg Chem 24, 1159.
- Ma DL*, Wu C, Wu KJ, Leung CH (Corresponding author)*. (2019) Iridium(III) complexes targeting apoptotic cell death in cancer cells. Molecules 24, 15, 2739.
- Zhang JT, Kang TS, Wong SY, Pei RJ*, Ma DL*, Leung CH (Corresponding author)*. (2019) An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent. Anal Biochem 580, 49.
- Leung CH (Corresponding author)*, Wu KJ, Li GD, Wu C, Ko CN, Ma DL*. (2019) Application of label-free techniques in microfluidic for biomolecules detection and circulating tumor cells analysis. Trends. Anal. Chem., 117, 78.
- Ko CN, Sun H, Wu KJ, Ren KN*, Leung CH, Ma DL*. (2019) A portable oligonucleotide-based microfluidic device for the detection of VEGF165 in a three-step suspended-droplet mode. Dalton Trans 48, 9824.
- Wu C, Wu KJ, Liu JB, Zhou XM, Leung CH (Corresponding author)*, Ma DL*. (2019) A dual–functional molecular strategy for in–situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes. Chem Comm 55, 6353. Front cover
- Wu KJ, Liu X, Wong SY, Zhou YY*, Ma DL*, Leung CH (Corresponding author)*. (2019) Synthesis and evaluation of dibenzothiophene analogues as Pin1 inhibitors for cervical cancer therapy. ACS Omega 4, 9228.
- Wang WH, Lu LH, Wu KJ, Liu JS, Leung CH, Wong CY*, Ma DL*. (2019) Long-lived iridium(III) complexes as luminescent probes for the detection of periodate in living cells. Sensor Actuat B Chem 288, 392.
- Ma DL*, Wong SY, Kang TS, Ng HP, Han QB, Leung CH (Corresponding author)*. (2019) Iridium(III)-based chemosensors for the detection of metal ions. Methods168, 3.
- Li GD, Boyle JW, Ko CN, Zeng W, Wong VKW, Wan JB, Chan PWH*, Ma DL*, Leung CH (Corresponding author)*. (2019) Aurone derivatives as Vps34 inhibitors that modulate autophagy. Acta Pharm Sin B 9, 537.
- Ma DL*, Wu C, Cheng SS, Lee FW, Han QB, Leung CH(Corresponding author)*. (2019) Development of natural product-conjugated metal complexes as cancer therapies. Int J Mol Sci 20, 341.
- Yang GJ, Ko CN, Zhong HJ, Leung CH (Corresponding author)*, Ma DL*. (2019) Structure-based discovery of a selective KDM5A inhibitor that exhibits anti-cancer activity via inducing cell cycle arrest and senescence in breast cancer cell lines. Cancers 11, 92.
- Bao WR, Li ZP, Zhang QW, Li LF, Liu HB, Ma DL, Leung CH, Lu AP, Bian ZX,* Han QB.* (2018) Astragalus polysaccharide RAP selectively attenuates paclitaxel-induced cytotoxicity towards RAW 264.7 cells by reversing cell cycle arrest and apoptosis. Front. Pharmacol 9, 1580.
- Yang GJ, Lei PM, Ma DL,* Leung CH (Corresponding author)*. (2018) Pharmacological inhibition of LSD1 for cancer treatment. Molecules 23, E3194.
- Ko CN, Li GD, Leung CH (Corresponding author)*, Ma DL*. (2019) Dual function luminescent transition metal complexes for cancer theranostics: the combination of diagnosis and therapy. Coord Chem Rev 381, 79.
- Kang TS, Ko CN, Zhang JT, Wu C, Wong CY, Ma DL,* Leung CH (Corresponding author)*. (2018) Rhodium(III)-based inhibitor of the JMJD3-H3K27me3 interaction and modulator of the inflammatory response. Inorg Chem 57, 14023.
- Ma DL,* NG HP, Wong SY, Vellaisamy K, Wu KJ, Leung CH (Corresponding author)*. (2018) Iridium(III) complexes as reaction based chemosensors for medical diagnostics. Dalton Trans 47, 15278.
- Vellaisamy K, Li GD, Wang WH, Leung CH (Corresponding author)*, Ma DL*. (2018) A long-lived peptide-conjugated iridium(III) complex as a luminescent probe and inhibitor of the cell migration mediator, formyl peptide receptor 2. Chem Sci 9, 8171. Front cover
- Kang TS, Zhang JT, Vellaisamy K, Ma DL,* Leung CH (Corresponding author).* (2018) Recent progress and developments of iridium-based compounds as probes for environmental analytes. Dalton Trans. 47, 13314.
- Wu C, Wu KJ, Kang TS, Wang HM, Leung CH, Liu JB,* Ma DL.* (2018) Iridium-based probe for luminescent nitric oxide monitoring in live cells. Sci Rep 8, 12467.
- Wu C, Liu JB, Li GD, Wong SY, Han QB, Leung CH, Ma DL.* (2018) Chemoselective detection of alkyl halides via an iridium(III) luminescent probe. Dyes Pigments 159, 479.
- He JB, Chen K, Hu ZM, Li K, Song W, Yu LY, Leung CH, Ma DL, Qiao X,* Ye M.* (2018) UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids. Chem Commun 54, 8594.
- Yang GJ, Wang WH, Mok SWF, Wu C, Law BYK, Miao XM, Wu KJ, Zhong HJ, Wong CY, Wong VKW,* Ma DL,* Leung CH (Corresponding author).* (2018) Selective inhibition of lysine-specific demethylase 5A (KDM5A) using a rhodium(III) complex for triple-negative breast cancer therapy. Angew Chem Int Ed 57, 13091. Inside back cover
- Li PH, Liu LH, Chang CC, Gao R, Leung CH, Ma DL, Wang HMD.* (2018) Silencing stem cell factor gene in fibroblasts to regulate paracrine factor productions and enhance c-Kit expression in melanocytes on melanogenesis. Int J Mol Sci 19, 1475.
- Liu JB, Vellaisamy K, Li GD, Yang C, Wong SY, Leung CH, Pu SZ,* Ma DL.* (2018) A long-lifetime iridium(III) complex for lysosome tracking with high specificity and a large Stokes shift. J Mater Chem B 6, 3855.
- Yang GJ, Zhong HJ, Ko CN, Yu WS, Vellaisamy K, Ye M, Ma DL,* Leung CH (Corresponding author).* (2018) Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells. Chem Commun 54, 2443. Front cover
- Wu KJ, Zhong HJ, Yang GJ, Wu C, Huang JM, Li GD, Ma DL,* Leung CH (Corresponding author).* (2018) A small molecule Pin 1 inhibitor blocks NF-κB signaling in prostate cancer cells. Chem Asian J 13, 275.
- Ma DL,* Wu C, Tang W, Gupta AR, Lee FW, Li GD, Leung CH (Corresponding author).* (2018) Recent advances in iridium(III) complex-assisted nanomaterials for biological applications. J Mater Chem B 6, 537.
- Vellaisamy K, Li GD, Ko CN, Zhong HJ, Fatima S, Kwan HY, Wong CY, Kwong WJ,* Tan WH,* Leung CH (Corresponding author),* Ma DL.* (2018) Cell imaging of dopamine receptor using agonist labeling iridium(III) complex. Chem Sci 9, 1119. Inside front cover
- Ma DL,* Wu C, Li GD, Leung CH (Corresponding author).* (2018) Group 8-9 metal-based luminescent chemosensors for protein biomarker detection. J Anal Test 2, 77.
- Wu KJ, Zhong HJ, Li GD, Liu CF, Wang HMD, Ma DL,* Leung CH (Corresponding author).* (2018) Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing. Eur J Med Chem 143, 1021.
- Liu JB, Wang WH, Li GD, Wang RX,* Leung CH (Corresponding author),* Ma DL.* (2017) A luminescent iridium(III) chemosensor for tandem detection of F− and Al3+. ACS Omega 2, 9150.
- Ng SW, Chung LH, Yeung CF, Lo HS, Shek HL, Kang TS, Leung CH, Ma DL, Wong CY.* (2018) Metalated chromene and chromone complexes: pH switchable metal-carbon bonding interaction, photo-triggerable chromone delivery application, and antioxidative activity. Chem Eur J 24, 1779.
- Wu C, Li GD, Han QB, Pei RJ, Liu JB,* Ma DL,* Leung CH (Corresponding author).* (2017) Real-time detection of oxalyl chloride based on a long lived iridium(III) probe. Dalton Trans 46, 17074.
- Lu L, Liu CF, Li GD, Liu LJ, Leung CH (Corresponding author),* Ma DL.* (2018) Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment. Sensor Actuat B Chem 257, 860.
- Wang WH, Vellaisamy K, Li GD, Wu C, Ko CN, Leung CH (Corresponding author),* Ma DL.* (2017) Development of a long-lived luminescence probe for visualizing β-galactosidase in ovarian carcinoma cells. Anal Chem 89, 11679.
- Dong ZZ, Yang C, Vellaisamy K, Li GD, Leung CH (Corresponding author),* Ma DL.* (2017) Construction of a nano biosensor for cyanide anion detection and its application in environmental and biological systems. ACS Sensors 2, 1517.
- Wang WH, Wu C, Yang C, Li GD, Han QB, Li SN, Lee MY, Leung CH, Ma DL.* (2018) A dual-functional luminescent probe for imaging H2S in living zebrafish and discrimination hypoxic cells from normoxic cells. Sensor Actuat B Chem 255, 1953.
- Wang Y, Guo GX, Feng YX, Long HY, Ma DL, Leung CH, Dong L,* Wang CM.* (2017) A tumour microenvironment-responsive polymeric complex for targeted depletion of tumour-associated macrophages (TAMs). J. Mater Chem B 5, 7307.
- Sun H, Li WB, Dong ZZ, Hu C, Leung CH (Corresponding author),* Ma DL,* Ren KN.* (2018) A suspending-droplet mode paper-based microfluidic platform for low-cost, rapid, and convenient detection of lead(II) ions in liquid solution. Biosens Bioelectron 99, 361.
- Liu JS, Dong ZZ, Yang C, Li GD, Wu C, Lee FW, Leung CH, Ma DL.* (2017) Turn-on luminescent probe for hydrogen peroxide sensing and imaging in living cells based on an iridium(III) complex−silver nanoparticle platform. Sci Rep 7, 8980.
- Leung CH, Hu H. (2017) Challenges and suggestions of blended learning for postgraduates: two case courses at ICMS of the University of Macau. eLFA 2017 Conference Proceeding
- Ko CN, Wu C, Li GD, Leung CH, Liu JB,* Ma DL.* (2017) A long-lived ferrocene-conjugated iridium(III) complex for sensitive turn-on luminescence detection of traces of DMSO in water and human serum. Anal Chim Acta 984, 193.
- Liang JX, Zhong HJ, Yang GJ, Vellaisamy K, Ma DL,* Leung CH (Corresponding author).* (2017) Recent development of transition metal complexes with in vivo antitumor activity. J Inorg Biochem 177, 276.
- Wang WH, Dong ZZ, Yang C, Li GD, Tse YC, Leung CH (Corresponding author),* Ma DL.* (2017) An iridium(III) complex-based chemosensor for the detection of thiourea in living cells. Sensor Actuat B Chem 251, 374.
- Liu LJ, Wang WH, Huang SY, Hong YJ, Li GD, Lin S, Tian JL, Cai ZW,* Wang HMD,* Ma DL,* Leung CH (Corresponding author).* (2017) Inhibition of the Ras/Raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium(III) metal-based compound. Chem Sci 8, 4756. Inside back cover
- Liu JS, Vellaisamy K, Yang GJ, Leung CH (Corresponding author),* Ma DL.* (2017) Luminescent turn-on detection of Hg(II) via the quenching of an iridium(III) complex by Hg(II)-mediated silver nanoparticles. Sci Rep 7, 3620.
- Ma DL,* Wu C, Dong ZZ, Tam WS, Wong SW, Yang C, Li GD, Leung CH (Corresponding author).* (2017) The development of G-quadruplex-based assays for the detection of small molecules and toxic substances. Chem Asian J 12, 1851.
- Wu C, Vellaisamy K, Yang GJ, Dong ZZ, Leung CH, Liu JB,* Ma DL.* (2017) A reaction-based luminescent switch-on sensor for the detection of OH ion in simulated wastewater. Dalton Trans 46, 6677.
- Wu KJ, Huang JM, Zhong HJ, Dong ZZ, Vellaisamy K, Lu JJ, Chen XP, Chiu P, Kwong DWJ, Han QB, Ma DL,* Leung CH (Corresponding author).* (2017) A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells. Plos One 12, e0177123.
- Ma DL,* Dong ZZ, Vellaisamy K, Cheung KM, Yang GJ, Leung CH (Corresponding author).* (2017) Luminescent strategies for label-free G-quadruplex-based enzyme activity sensing. Chem Rec 17, 1135.
- Ko CN, Yang C, Lin S, Li SN, Dong ZZ, Liu JB,* Lee SMY,* Leung CH (Corresponding author),* Ma DL.* (2017) A long-lived phosphorescence iridium(III) complex as a switch on-off-on probe for live zebrafish monitoring of endogenous sulfide generation. Biosens Bioelectron 94, 575.
- Wang WH, Dong ZZ, Yang GJ, Leung CH, Lin S,* Ma DL.* (2017) A long-lived iridium(III) chemosensor for the real-time detection of GHB. J Mater Chem B 5, 2739.
- Kang TS, Wang WH, Zhong HJ, Dong ZZ, Huang Q, Mok SWF, Leung CH (Corresponding author),* Wong VKW,* Ma DL.* (2017) An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB. Cancer Lett 396, 76.
- Dong ZZ, Lu LH, Wang WH, Li GD, Kang TS, Han QB, Leung CH (Corresponding author),* Ma DL.* (2017) Luminescent detection of nicking endonuclease Nb.BsmI activity by using a G-quadruplex-selective iridium(III) complex in aqueous solution. Sensor Actuat B Chem 246, 826.
- Yang C, Wang WH, Liang JX, Li GD, Vellaisamy K, Wong CY, Ma DL,* Leung CH (Corresponding author).* (2017) A rhodium(III)-based inhibitor of lysine-specific histone demethylase 1 as an epigenetic modulator in prostate cancer cells. J Med Chem 60, 2597.
- Wang WH, Yang C, Lin S, Vellaisamy K, Li GD, Tan WH,* Leung CH (Corresponding author),* Ma DL.* (2017) First synthesis of an oridonin-conjugated iridium(III) complex for the intracellular tracking of NF-κB in living cells. Chem Eur J 23, 4929.
- Yang C, Wang WH, Li GD, Zhong HJ, Dong ZZ, Wong CY, Kwong DWJ, Ma DL,* Leung CH (Corresponding author).* (2017) Anticancer osmium complexes inhibitor of the HIF-1α and p300 protein-protein interaction. Sci Rep 7, 42860.
- Wang YF, Xu YL, Tang ZH, Li T, Zhang LL, Chen XP, Lu JH, Leung CH, Ma DL, Qiang WA, Wang YT, Lu JJ.* (2017) Baicalein induces Beclin 1- and extracellular signal-regulated kinase-dependent autophagy in ovarian cancer cells. Am J Chin Med 45, 123.
- Liu CF, Yang C, Lu L, Wang WH, Tan WH,* Leung CH (Corresponding author),* Ma DL.* (2017) Luminescent iridium(III) complexes as COX-2-specific imaging agents in cancer cells. Chem Commun 53, 2822. Back cover
- Miao XM, Ko CN, Vellaisamy K, Li ZB, Yang GJ, Leung CH, Ma DL.* (2017) A cyclometalated iridium(III) complex used as a conductor for the electrochemical sensing of IFN-γ. Sci Rep 7, 42740.
- Dong ZZ, Lu L, Ko CN, Yang C, Li S, Lee MY, Leung CH (Corresponding author),* Ma DL.* (2017) A MnO2 nanosheet-assisted GSH detection platform by using iridium(III) complex as a switch-on luminescent probe. Nanoscale 9, 4631. Inside front cover
- Wei W, Li ZP, Zhu T, Fung HY, Wong TL, Wen X, Ma DL, Leung CH, Han QB.* (2017) Anti-fatigue effects of the unique polysaccharide marker of Dendrobium officinale on BALB/c mice. Molecules 22, 155.
- Chan WI, Zhang GP, Li X, Leung CH, Ma DL, Dong L, Wang CM.* (2017) Carrageenan activates monocytes via type-specific binding with Interleukin-8: An implication for design of immuno-active biomaterials. Biomater Sci 5, 403.
- Fung HY, Lang Y, Ho HM, Wong TL, Ma DL, Leung CH, Han QB.* (2017) Comprehensive quantitative analysis of 32 chemical ingredients of a Chinese patent drug Sanhuang Tablet. Molecules 22, 111.
- Liu JB,* Yang C, Ko CN, Vellaisamy K, Yang BR, Lee MY, Leung CH, Ma DL.* (2017) A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish. Sensor Actuat B Chem 243, 971.
- Zhong HJ,* Wang WH, Kang TS, Yan H, Yang YL, Xu LP, Wang YQ, Ma DL,* Leung CH (Corresponding author).* (2016) A rhodium(III) complex as an inhibitor of neural precursor cell expressed, developmentally down-regulated 8-activating enzyme with in vivo activity against inflammatory bowel disease. J Med Chem 60, 497.
- Lin S, Wang WH, Hu C, Yang GJ, Ko CN, Ren KN,* Leung CH (Corresponding author),* Ma DL.* (2017) The application of G-quadruplex based assay with an iridium(III) complex to arsenic ion detection and its utilization in a microfluidic chip. J Mater Chem B 5, 479.
- Tejo C, Tirtorahardjo D, Day D, Ma DL, Leung CH, Chan PWH.* (2017) Brønsted Base-Mediated Aziridination of 2-Alkyl-Substituted-1,3-Dicarbonyl Compounds and 2-Acyl-Substituted-1,4-Dicarbonyl Compounds by Iminoiodanes. Aust J Chem 70, 430.
- Kang TS, Wang WH, Zhong HJ, Liang JX, Ko CN, Lu JJ, Chen XP, Ma DL,* Leung CH (Corresponding author).* (2017) A rhodium(III)-based inhibitor of autotaxin with anti proliferative activity. Biochim Biophys Acta Gen Subjects 1861, 256.
- Ma DL,* Lin S, Wang WH, Yang C, Leung CH (Corresponding author).* (2017) Luminescent chemosensors by using cyclometalated iridium(III) complexes and their applications. Chem Sci 8, 878.
- Li T, Chen X, Chen XP, Ma DL, Leung CH, Lu JJ.* (2016) Platycodin D potentiates proliferation inhibition and apoptosis induction upon AKT inhibition via feedback blockade in non-small cell lung cancer cells. Sci Rep 6, 418.
- Niu YN, Sun W, Lu JJ, Ma DL, Leung CH, Pei LX, Chen XP.* (2016) PTEN activation by DNA damage induces protective autophagy in response to cucurbitacin B in hepatocellular carcinoma cells. Oxid Med Cell Longev 2016, 1.
- Liu JB,* Liu LJ, Dong ZZ, Yang GJ, Leung CH, Ma DL.* (2016) An aldol reaction-based Iridium(III) chemosensor for the visualization of proline in living cells. Sci Rep 6, 192.
- Liu LJ, Wang WH, Kang TS, Liang JX, Liu CF, Kwong DWJ, Wong VKW, Ma DL,* Leung CH (Corresponding author).* (2016) Antagonizing STAT5B dimerization with an osmium complex. Sci Rep 6, 361.
- Lu L, Wang WH, Yang C, Kang TS, Leung CH (Corresponding author),* Ma DL.* (2016) Iridium(III) complexes with 1,10-Phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection. J. Mater Chem B 4, 6791.
- Lin S, Lu L, Kang TS, Mergny JL, Leung CH (Corresponding author),* Ma DL.* (2016) The interaction of an iridium(III) complex with G-quadruplex DNA and its application in luminescent switch-on detection of Siglec-5. Anal Chem 88, 10290.
- Yang C, Wang WH, Chen LM, Liang JX, Lin S, Lee SMY, Ma DL,* Leung CH (Corresponding author).* (2016) Discovery of a VHL and HIF1α interaction inhibitor with in vivo angiogenic activity by structure-based virtual screening. Chem Commun 52, 12837.
- Liu LJ, Wang WH, Zhong Z, Lin S, Lu L, Wang YT, Ma DL,* Leung CH (Corresponding author).* (2016) Inhibition of TLR1/2 dimerization by enantiomers of metal complexes. Chem Commun 52, 12278. Front cover
- Hu C, Lin S, Li WB, Sun H, Chen YF, Chan CW, Leung CH, Ma DL,* Wu HK,* Ren KN.* (2016) A One-Step Strategy for Ultra-Fast and Low Cost Mass Production of Plastic Membrane Microfluidic Chips. Lab Chip 16, 3909. Front cover
- Lin S, Lu L, Liu JB, Liu CF, Kang TS, Yang C, Leung CH (Corresponding author),* Ma DL.* (2017) A G-quadruplex-selective luminescent iridium(III) complex and its application by long lifetime. Biochim Biophys Acta Gen Subjects 1861, 1448.
- Wu CS, Wei KL, Chou JL, Lu CK, Hsieh CC, Lin JMJ, Deng YF, Hsu WT, Wang HMD, Leung CH, Ma DL, Li C, Chan MWY.* (2016) Aberrant JAK/STAT signaling suppresses TFF1 and TFF2 through epigenetic silencing of GATA6 in gastric cancer. Int J Mol Sci 17, 1467.
- Xu SW, Law BYK, Mok SWF, Leung ELH, Fan XX, Coghi PS, Zeng W, Leung CH, Ma DL, Liu L,* Wong VKW.* (2016) Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol. Int J Oncol 49, 1576.
- Wang M, Wang WH, Liu CF, Liu JB, Kang TS, Leung CH, Ma DL.* (2017) A luminescent switch-on assay for the detection of specific gene deletion using G-quadruplex DNA and silver nanoclusters. Mater Chem Front 1, 128.
- Lin S, Kang TS, Lu L, Wang WH, Ma DL,* Leung CH (Corresponding author).* (2016) A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity. Biosens Bioelectron 86, 849.
- Ma DL,* Wang M, Liu CF, Miao XM, Kang TS, Leung CH (Corresponding author).* (2016) Metal complexes for the detection of disease-related protein biomarkers. Coord Chem Rev 324, 90.
- Ren GW, Luo WW, Sun W, Niu YN, Ma DL, Leung CH, Wang YT, Lu JJ,* Chen XP.* (2016) Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells. Phytomedicine 23, 939.
- Miao XM, Wang WH, Kang TS, Liu JB, Shiu KK, Leung CH, Ma DL.* (2016) Ultrasensitive electrochemical detection of miRNA-21 by using an iridium(III) complex as catalyst. Biosens Bioelectron 86, 454.
- Li XJ, Bao WR, Leung CH, Ma DL, Zhang G, Lu AP, Wang SC,* Han QB.* (2016) Chemical structure and immunomodulating activities of an α-glucan purified from Lobelia chinensis Lour. Molecules 21, 779.
- Li PH, Chiu YP, Shih CC, Wen ZH, Ibeto LK, Huang SH, Chiu CC, Ma DL, Leung CH, Chang YN, Wang HM.* (2016) Bio-functional activities of Equisetum ramosissimum extract: protective effects against oxidation, melanoma and melanogenesis. Oxid Med Cell Longev 2016, 1.
- Lu L,* Mao ZF, Kang TS, Leung CH (Corresponding author),* Ma DL.* (2016) A versatile nanomachine for the sensitive detection of platelet-derived growth factor-BB utilizing a G-quadruplex-selective iridium(III) complex. Biosens Bioelectron 85, 300.
- Ma GX, Luo WW, Lu JJ, Ma DL, Leung CH, Wang YT, Chen XP.* (2016) Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells. Chem Biol Interact 253, 1.
- Tian Y, Zhang L, Shen J, Wu L, He HZ, Ma DL, Leung CH, Wu W, Fan Q, Huang W, Wang L. (2016) An individual nanocube-based plasmonic biosensor for real-time monitoring the structural switch of the telomeric G-quadruplex. Small 12, 2913.
- Miao XM, Yang C, Leung CH (Corresponding author),* Ma DL.* (2016) Application of iridium(III) complex in label-free and non-enzymatic electrochemical detection of hydrogen peroxide based on a novel “on-off-on” switch platform. Sci Rep 6, 25774.
- Wong TL, An YQ, Yan BC, Yue RQ, Zhang TB, Ho HM, Ren TJ, Fung HY, Ma DL, Leung CH, Liu ZL, Pu JX,* Han QB,* and Sun HD. (2016) Comprehensive quantitative analysis of Chinese patent drug YinHuang Drop Pill by ultra high-performance liquid chromatography quadrupole time of flight mass spectrometry. J Pharmaceut Biomed 125, 415.
- Kang TS, Mao ZF, Ng CT, Wang M, Wang WH, Wang CM, Lee SMY, Wang YT, Leung CH (Corresponding author),* Ma DL.* (2016) Identification of an Iridium(III)-Based Inhibitor of Tumor Necrosis Factor-α. J Med Chem 59, 4026
- Leung CH (Corresponding author),* Liu LJ, Leung KH, Ma DL.* (2016) Epigenetic modulation by inorganic metal complexes. Coord Chem Rev 319, 25.
- Lu L, Wang WH, Wang M, Kang TS, Lu JJ, Chen XP, Han QB, Leung CH, Ma DL.* (2016) A Luminescent G-Quadruplex-Selective Iridium(III) Complex for the Label-Free Detection of Lysozyme. J Mater Chem B 4, 2407.
- Zhong HJ, Lee BR, Boyle JW, Wang WH, Ma DL,* Chan PWH,* Leung CH (Corresponding author).* (2016) Structure-based screening and optimization of cytisine derivatives as inhibitors of the menin-MLL interaction. Chem Commun 52, 5788. Front cover
- Ma DL,* Wang M, Mao ZF, Kang TS, Han QB, Chan PWH, Leung CH (Corresponding author).* (2017) Utilization of G-quadruplex forming aptamers for the construction of luminescence sensing platforms. ChemPlusChem 82, 8. One of the most accessed articles in 2017
- Guo SH, Luo WW, Liu LJ, Pang XC, Zhu H, Liu A, Lu JJ, Ma DL, Leung CH, Wang YT, Chen XP.* (2016) Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells. J Drug Target 1, 1.
- Mao ZF, Liu JB, Kang TS, Wang WH, Han QB, Wang CM, Leung CH (Corresponding author),* Ma DL.* (2016) An Ir(III) complex chemosensor for the detection of thiols. Sci Technol Adv Mat 17, 109.
- Lu L, Wang M, Mao ZF, Kang TS, Chen XP, Lu JJ, Leung CH, Ma DL.* (2016) A novel dinuclear iridium(III) complex as a G-quadruplex-selective probe for the luminescent switch-on detection of transcription factor HIF-1α. Sci Rep 6, 22458.
- Mao ZF, Wang M, Liu JB, Liu LJ, Lee SMY, Leung CH (Corresponding author),* Ma DL.* (2016) A long lifetime switch-on iridium (III) chemosensor for the visualization of cysteine in live zebrafish. Chem Commun 52, 4450. Inside front cover
- Liu LJ, He BY, Miles JA, Wang WH, Mao ZF, Che WI, Lu JJ, Chen XP, Wilson AJ, Ma DL,* Leung CH (Corresponding author).* (2016) Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium (III) compounds. Oncotarget 7, 13965.
- Wang M, Mao ZF, Kang TS, Wong CY, Mergny JL, Leung CH (Corresponding author),* Ma DL.* (2016) Conjugating a groove-binding motif to Ir(III) complex for the enhancement of G-quadruplex probe behavior. Chem Sci 7, 2516. Back cover
- Wang WH, Mao ZF, Wang M, Liu LJ, Kwong DWJ, Leung CH (Corresponding author),* Ma DL.* (2016) A long lifetime luminescent iridium(III) complex chemosensor for selective switch-on detection of Al3+ ions. Chem Commun 52, 3611. Inside front cover
- Ma DL,* Wang M, Mao ZF, Yang C, Chen XP, Lu JJ, Han QB, Leung CH (Corresponding author).* (2016) A tutorial review for employing enzymes for the construction of G-quadruplex-based sensing platforms. Anal Chim Acta 913, 41.
- Sun W, Bao JL, Lin W, Gao HW, Zhao WW, Zhang QW, Leung CH, Ma DL, Lu JJ, Chen XP.* (2016) 2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells. Free Radical Bio Med 92, 61.
- Wei W, Feng L, Bao WR, Ma DL, Leung CH, Nie SP,* Han QB.* (2016) Structure characterization and immunomodulating effects of the polysaccharides isolated from Dendrobium officinale. J Agr Food Chem 64, 881.
- Wei W, Xiao HT, Bao WR, Ma DL, Leung CH, Han XQ, Ko CH, Lau CBS, Wong CK, Fung KP, Leung PC, Bian ZX,* Han QB.* (2016) TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells. J Ethnopharmacol 179, 243.
- Ma DL,* Wang M, Mao ZF, Yang C, Ng CT, Leung CH (Corresponding author).* (2016) Rhodium complexes as therapeutic agents. Dalton Trans 45, 2762.
- Lin XX, Leung KH, Lin L, Lin LY, Lin S, Leung CH, Ma DL,* Lin JM.* (2016) Determination of cell metabolite VEGF165 and dynamic analysis of protein–DNA interactions by combination of microfluidic technique and luminescent switch-on probe. Biosens Bioelectron 79, 41.
- Wang M, Wang WH, Kang TS, Leung CH, Ma DL.* (2016) Development of an iridium(III) complex as a G-quadruplex probe and its application for the G-quadruplex-based luminescent detection of picomolar insulin. Anal Chem 88, 981.
- Wang WH, Kang TS, Chan PWH, Lu JJ, Chen XP, Leung CH (Corresponding author),* Ma DL.* (2015) A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T-Hg2+-T mismatched DNA. Sci Technol Adv Mat 6, 065004.
- Lu L, Zhong HJ, He B, Leung CH (Corresponding author),* Ma DL.* (2016) Development of a luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of adenosine. Sci Rep 6, 19368.
- Tang ZH, Zhang LL, Li T, Lu JH, Ma DL, Leung CH, Chen XP, Jiang HL, Wang YT, Lu JJ.* (2015) Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells. Oncotarget 6, 4391.
- Lin S, Yang C, Mao Z, He BY, Wang YT, Leung CH (Corresponding author),* Ma DL.* (2016) A G-pentaplex-based assay for Cs+ ions in aqueous solution using a luminescent Ir(III) complex. Biosens Bioelectron 77, 609.
- Leung KH, He BY, Yang C, Leung CH (Corresponding author),* Wang HM,* Ma DL.* (2015) Development of an aptamer-based sensing platform for metal ions, proteins and small molecules through terminal deoxynucleotidyl transferase-induced G-quadruplex formation. ACS Appl Mater Interfaces 7, 24046.
- Chung LH, Lo HS, Ma DL, Leung CH, Wong CY.* (2015) Luminescent iridium(III) complexes supported by N-heterocyclic carbene-based C^C^C-pincer ligands and aromatic diimines. Sci Rep 5,15394.
- Li T, Xu XH, Tang ZH, Wang YF, Leung CH, Ma DL, Chen XP, Wang YT, Chen Y, Lu JJ.* (2015) Platycodin D induces apoptosis and triggers a extracellular signal-regulated kinase and c-Jun N-terminal kinase-mediated autophagy in hepatocellular carcinoma BET-7402 cells. Acta Pharmacol Sin 36,1503.
- Lin S, He B, Yang C, Leung CH (Corresponding author),* Mergny JL,* Ma DL.* (2015) Luminescence switch-on assay of interferon-gamma using a G-quadruplex-selective iridium(III) complex. Chem Commun 51, 16033. Front cover
- Ma DL*, Wang M, He B, Yang C, Wang H, Leung CH (Corresponding author).* (2015) A luminescent cocaine detection platform using a split G-quadruplex-selective iridium(III) complex and a three-way DNA junction architecture. ACS Appl Mater Interfaces 7, 19060.
- Liu LJ, Lu L, Zhong HJ, He BY, Kwong D, Ma DL,* Leung CH (Corresponding author).* (2015) An Iridium(Ⅲ) complex inhibits JMJD2 activities and acts as a potential epigenetic modulator. J Med Chem 16, 6697.
- Zhong HJ, Lu L, Wong CL-C , Peng C, Yan SC, Ma DL,* Cai ZW,* Wang HMD* and Leung CH (Corresponding author).* (2015) An iridium(III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent. Chem Sci 6, 5400. Inside front cover
- Gao HW, Sun W, Zhao WW, Hao WH, Leung CH, Lu JJ, Chen XP.* (2015) Total tanshinones-induced apoptosis and autophagy via reactive oxygen species in lung cancer 95D cells. Am J Chin Med 43, 1.
- Tejo C, Sim XR, Lee BR, Ayers BJJ, Leung CH, Ma DL, Chan PWH.* (2015) Iminoiodane- and brønsted base-mediated cross dehydrogenative coupling of cyclic ethers with 1,3-dicarbonyl compounds. Molecules 20, 13336.
- Ma DL,* Zhang Z, Wang M, Lu L, Zhong HJ, Leung CH (Corresponding author).* (2015) Recent developments in G-quadruplex probes. Chem Biol 6, 812. Front cover
- Lu L, Liu LJ, Chao WC, Zhong HJ, Wang M, Chen XP, Lu JJ, Li RN,* Ma DL,* Leung CH (Corresponding author).* (2015) Identification of an iridium(III) complex with anti-bacterial and anti-cancer activity. Sci Rep 5, 14544.
- Zhong Z, Liu LJ, Dong ZQ, Lu L, Wang M, Leung CH (Corresponding author),* Ma DL,* Wang YT.* (2015) Structure-based discovery of an immunomodulatory inhibitor of TLR1-TLR2 heterodimerization from a natural product-like database. Chem Commun 51, 11178.
- Lin S, Gao W, Tian Z, Yang C, Lu L, Mergny JL,* Leung CH (Corresponding author),* Ma DL.* (2015) Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe. Chem Sci 6, 4284.
- Lu L, Wang M, Liu LJ, Wong CY, Leung CH (Corresponding author),* Ma DL.* (2015) A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. Chem Commun 49, 9953.
- Lu L, Zhong HJ, Wang M, Ho SL, Li HW,* Leung CH (Corresponding author),* Ma DL.* (2015) Inhibition of beta-amyloid fibrillation by luminescent iridium(III) complex probes. Sci Rep 5, 14619.
- Ma DL,* Lin S, Lu L, Wang M, Hu C, Liu LJ, Ren K,* Leung CH (Corresponding author).* (2015) G-quadruplex-based logic gates for HgII and AgI ions employing a luminescent iridium(III) complex and extension of metal-mediated based pairs by polymerase. J Mater Chem B 24, 4780. Front cover
- Lu L, Wang M, Liu LJ, Leung CH (Corresponding author),* Ma DL.* (2015) Label-free luminescent switch-on probe for ochratoxin A detection using a G-quadruplex-selective iridium(III) complex. ACS Appl Mater Interfaces 7, 8313.
- Susanti D, Liu LJ, Rao W, Lin S, Ma DL,* Leung CH (Corresponding author),* Chan PWH.* (2015) Gold-catalyzed cycloisomerization and Diels-Alder reaction of 1,4,9-dienyne esters with pro-inflammatory cytokine antagonist activity. Chem Eur J 21, 9111.
- Ma DL,* Wang M, Lin S, Han QB, Leung CH. (2015) Recent development of G-quadruplex probes for cellular imaging. Curr Top Med Chem 15, 1957.
- Wong CY,* Chung LH, He B, Leung CH (Corresponding author),* Ma DL.* (2015) Dual inhibition and monitoring of beta-amyloid fibrillation by a luminescent iridium(III) complex. Curr Alzheimer Res 12, 439.
- Chan SLF,* Lam TL, Lu L, Yan SC, Leung CH, Ma DL.* (2015) A novel tetradentate ruthenium(II) complex containing tris(2-pyridylmethyl)amine (tpa) as an inhibitor of beta-amyloid fibrillation. Curr Alzheimer Res 12, 434.
- Teo WT, Koh SWY, Ayers BJ, Ma DL, Leung CH, Chan PWH.* (2015) Silver triflate-catalyzed cyclopropyl carbinol rearrangement for benzo[b]oxepine and 2H-Chromene synthesis. Eur J Org Chem 20, 4447
- Ma DL,* Wang M, Wang W, Lu L, Wang HMD, Leung CH. (2015) A label-free oligonucleotide-based "OR" logic gate using an Ir(II) complex as a luminescent switch-on probe. Science Let 4, 180.
- Hseu YC, Lin YC, Chen CY, Chou HY, Ma DL, Leung CH, Wen ZH, Wang HMD.* (2015) Synergistic effects of linderanolide B combined with arbutin, PTU or kojic acid on tyrosinase inhibition. Curr Pharm Biotechnol 1, 1.
- Ma DL,* Leung CH (Corresponding author).* (2015) Small molecule therapeutics for alzheimer’s disease. Curr Alzheimer Res 12, 400. Editorial article
- Tsui WK, Chung LH, Wong MMK, Tsang WH, Lo HS, Liu YX, Leung CH, Ma DL, Chiu SK, Wong CY.* (2015) Luminescent ruthenium(II) complex bearing bipyridine and N-Heterocyclic carbene-based C^N^C pincer ligand for live-cell imaging of endocytosis. Sci Rep 5, 9070.
- Leung KH, He HZ, Zhong HJ, Lin S, Wang YT, Ma DL,* Leung CH (Corresponding author).* (2015) Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe. Chem Sci 6, 2166. Front cover
- Wang M, He B, Leung CH, Mergny JL,* Ma DL.* (2015) Label -free luminescent detection of LMP1 gene delection using an intermolecular G-quadruplex-based switch-on probe. Biosens Bioelectron 70, 338.
- Lee MG, Kuo SY, Yen SY, Leung CH, Ma DL, Wen Z, Wang HM.* (2015) Identification of Cinnamomum osmophloeum Kanehira extracts on tyrosinase suppressor, antioxidant and wound repair promoter. Sci World J 2015, 1.
- Leung CH (Corresponding author),* Liu LJ, Lu L, He B, Kwong DWJ, Wong CY,* Ma DL.* (2015) A metal-based tumour necrosis factor-alpha converting enzyme inhibitor. Chem Commun 51, 3973. Front cover
- Leung CH (Corresponding author),* Lin S, Zhong HJ, Ma DL.* (2015) Metal complexes as potential modulators of inflammatory and autoimmune responses. Chem Sci 6, 871. Inside front cover One of the twenty-five most downloaded in Q4 2015
- Leung CH (Corresponding author),* Ma DL.* (2015) Recent advances in virtual screening for drug discovery. Methods 71, 1.Editorial article Front cover
- Liu LJ, Leung KH, Lin S, Chan DSH, Susanti D, Rao W, Chan PWH,* Ma DL,* Leung CH (Corresponding author).* (2015) Pharmacophore modeling for the identification of small-molecule inhibitors of TACE. Methods 71, 92.
- Zhong HJ, Leung KH, Lin S, Chan DSH, Han QB, Chan SLF, Ma DL,* Leung CH (Corresponding author).* (2015) Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme. Methods 71, 71.
- Leung KH, Liu LJ, Lin S, Lu L, Zhong HJ, Susanti D, Rao W, Wang M, Che WI, Chan DSH, Leung CH (Corresponding author),* Chan PWH,* Ma DL.* (2015) Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening. Methods 71, 38.
- Zhong HJ, Lin S, Tam IL, Lu L, Chan DSH, Ma DL,* Leung CH (Corresponding author).* (2015) In silico identification of natural product inhibitors of JAK2. Methods 71, 21.
- Ma DL,* Lu L, He BY, Leung CH. (2015) A G-triplex luminescent switch-on probe for the detection of Mung Bean nuclease activity. J Mater Chem B 3, 348.
- Tang K, Lu SY, Ma DL, Leung CH, Lee SS, Lin SW, Wang HMD.* (2015) A review on common ingredients of periocular cosmetics and their hazards. Curr Org Chem 19, 1.
- Ma DL,* Chan DSH, Leung CH (Corresponding author).* (2014) Group 9 organometallic compounds for therapeutic and bioanalytical applications. Acc Chem Res 47, 3614.
- Wang M, Leung KH, LIn S, Chan DSH, Kwong DWJ,* Leung CH (Corresponding author),* Ma DL.* (2014) A colorimetric chemosensor for Cu2+ ion detection based on an iridium(III) complex. Sci Rep 4, 6794.
- Wong CY,* Chung LH, Lin S, Chan DSH, Leung CH, Ma DL.* (2014) A ruthenium(II) complex supported by trithiacyclononane and aromatic diimine ligand as luminescent switch-on probe for biomolecule detection and protein staining. Sci Rep 4, 7136.
- Wang M, Leung KH, Lin S, Chan DSH, Leung CH, Ma DL.* (2014) A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ ions based on the exonuclease III-mediated digestion of C-Ag+-C DNA. J Mater Chem B 2, 6467.
- Zhang X,* Teo JW, Ma DL, Leung CH, Chan PWH.* (2014) Ytterbium(III) triflate-catalyzed annulation of propargylic 1,4-diols with aryl sulfonamides to highly substituted pyrrole derivatives. Tetrahedron Lett 55, 6703.
- Lu L, He HZ, Zhong HJ, Liu LJ, Chan DSH, Leung CH, Ma DL.* (2014) Luminescent detection of human serum albumin in aqueous solution using a cyclometalled iridium(III) complex. Sens Actuators B Chem 201, 177.
- Liu MS, Chau SL, Ma DL, Leung CH, Bian ZX, Lu AP, Xu HX,* Han QB.* (2014) Using two-phase solvent systems for sample pretreatment increases yield of counter-current chromatography: Anemarrhena asphodeloides saponins, a case study. Sep Purif Technol 138, 138.
- Lin S, He B, Chan DSH, Chan PWH, Leung CH, Ma DL.* (2014) A G-quadruplex-based platform for the detection of Hg2+ ions using a luminescent iridium(III) complex. RSC Adv 4, 54826.
- Lu L, Chan DSH, Kwong DWJ, He HZ,* Leung CH (Corresponding author),* Ma DL.* (2014) Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe. Chem Sci 5, 4561. Inside front cover
- Ma DL,* Chan DSH, Wei G, Zhong HJ, Yang H, Leung LT, Gullen EA, Chiu P,* Cheng YC,* Leung CH (Corresponding author).* (2014) Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library. Chem Commun 50, 13885. Inside front cover
- Zhang TB, Yue RQ, Xu J, Ho HM, Ma DL, Leung CH, Chau SL, Zhao ZZ, Chen HB,* Han QB.* (2014) Comprehensive quantitative analysis of Shuang-Huang-Lian oral liquid using UHPLC-Q-TOF-MS and HPLC-ELSD. J Pharm Biomed Anal 102, 1.
- Ma DL,* He HZ, Zhong HJ, Lin S, Chan DSH, Wang L, Lee SMY, Leung CH, Wong CY.* (2014) Visualization of Zn2+ ions in live zebrafish using a luminescent iridium(III) chemosensor. ACS Appl Mater Interfaces 6, 14008.
- Ma DL,* Liu LJ, Leung KH, Chen YT, Zhong HJ, Chan DSH, Wang HMD,* Leung CH (Corresponding author).* (2014) Antagonising STAT3 dimerization with a rhodium(III) complex. Angew Chem Int Ed 53, 9178. Back cover Selected as very important paper Highlighted by SciBX, Nature Publishing Group, 2014, 7(26)
- Liu LJ, Lin S, Chan DSH, Vong CT, Hoi PM, Wong CY, Ma DL,* Leung CH (Corresponding author).* (2014) A rhodium(III) complex inhibits LPS-induced nitric oxide production and angiogenic activity in cellulo. J Inorg Biochem 140, 23.
- Chung LH, Yeung CF, Ma DL, Leung CH, Wong CY.* (2014) Metal-Indolizine Zwitterion complexes as a new class of organometallic material: a spectroscopic and theoretical investigation. Organometallics 33, 3443.
- Zhang X,* Teo WT, Rao W, Ma DL, Leung CH, Chan PWH.* (2014) Synthesis of highly substituted indene derivatives by Brnsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols. Tetrahedron Lett 55, 3881.
- Ma DL,* Leung CH (Corresponding author).* (2014) Structure-Based Discovery of Natural Product-Like Protein Inhibitors. Austin J Bioorg Org Chem 1, 2. Editorial Article
- Ma DL,* Lin S, Leung KH, Zhong HZ, Liu LJ, Chan DSH, Bourdoncle A, Mergny JL, Wang HMD,* Leung CH (Corresponding author).* (2014) An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex. Nanoscale 6, 8489. Front cover
- Liu LJ, Leung KH, Chan DSH, Wang YT, Ma DL,* Leung CH (Corresponding author).* (2014) Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening. Cell Death Dis 5, e1293.
- Zhong HJ, Liu LJ, Chan DSH, Wang HM, Chan PWH, Ma DL,* Leung CH (Corresponding author).* (2014) Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme. Biochimie 102, 211
- Ma DL,* He HZ, Chan DSH, Wong CY, Leung CH. (2014) A colorimetric and luminescent dual-modal assay for Cu(II) ion detection using an iridium(III) complex. Plos One 9, e99930.
- He HZ, Leung KH, Wang W, Chan DSH, Leung CH, Ma DL.* (2014) Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe. Chem Commun 50, 5313. Inside front cover
- Zhong HJ, Leung KH, Liu LJ, Lu L, Chan DSH, Leung CH (Corresponding author),* Ma DL.* (2014) Antagonsism of mTOR activity by a kinetically inert rhodium(III) complex. ChemPlusChem 79, 508. One of the top 20 most cited articles published in 2014 or 2015
- Zhong HJ, Liu LJ, Chong CM, Lu L, Ai Z, Wang M, Chan DSH, Chan PWH, Lee SMY, Ma DL,* Leung CH (Corresponding author).* (2014) Discovery of a natural product-like iNOS inhibitor by molecular docking with potential neuroprotective effects in vivo. Plos One 4, e92905.
- Leung KH, He HZ, Wang W, Zhong HJ, Chan DSH, Leung CH (Corresponding author),* Ma DL.* (2013) Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex. ACS Appl Mater Interfaces 5, 12249.
- Ma DL,* Leung CH (Corresponding author).* (2013) Future frontiers in diversity-oriented synthesis. Organic Chem Curr Res 2, 5. Editorial article
- Leung CH, Chan DSH, Zhong HJ, Lu L, Ma DL.* (2013) Luminescent and colorimetric strategies for the label-free DNA-based detection of enzyme activity. Brief Funct Genomics 12, 525.
- Ma DL,* Leung CH (Corresponding author).* (2013) Recent advances in DNA-based biosensor. Methods 64, 183.Editorial article Front cover
- He HZ, Chan WI, Mak TY, Liu LJ, Wang M, Chan DSH, Ma DL,* Leung CH (Corresponding author).* (2013) Detection of 3’-5’ exonuclease activity using a metal-based luminescent switch-on probe. Methods 64, 218.
- Leung KH, He HZ, Zhong HJ, Lu L, Chan DSH, Ma DL,* Leung CH (Corresponding author).* (2013) A highly sensitive G-quadruplex-based luminescent switch-on probe for the detection of polymerase 3’ to 5’ proofreading activity. Methods 64, 224.
- He HZ, Wang M, Chan DSH, Leung CH, Qiu JW, Ma DL.* (2013) A label-free G-quadruplex-based luminescent switch-on assay for the selective detection of histidine. Methods 64, 205.
- He HZ, Wang M, Chan DSH, Leung CH, Lin X, Lin JM, Ma DL.* (2013) A parallel G-quadrulplex-selective luminescent probe for the detection of nanomolar calcium(II) ion. Methods 64, 212.
- Leung CH (Corresponding author),* (2013) Zhong HJ, He HZ, Lu L, Chan DSH, Ma DL.* Luminescent oligonucleotide-based detection of enzymes involved with DNA repair. Chem Sci 4, 3781.
- Leung KH, Lu L, Wang M, Mak TY, Chan DSH, Leung CH, Ma DL.* (2013) A label-free luminescent switch-on assay for ATP using a G-quadruplex-selective iridium(III) complex. Plos One 10, e77921.
- Leung CH (Corresponding author),* He HZ, Liu LJ, Wang M, Chan DSH, Ma DL.* (2013) Metal complexes as inhibitors of transcription factor activity. Coord. Chem. Rev., 257, 3139.
- Ma DL,* Chan DSH, Leung CH. (2013) Future frontiers in small molecule inhibitors of protein-protein interactions. International Journal of Bioorgannic Chemistry & Molecular Biology, 1, 201.
Editorial article - Ma DL,* He HZ, Chan DSH, Leung CH. (2013) Simple DNA-based logic gates responding to biomolecules and metal ions. Chem. Sci., 4, 3366.
- Leung CH (Corresponding author),* Zhong HJ, Chan DSH, Ma DL.* (2013) Bioactive iridium and rhodium complexes as therapeutic agents. Coord. Chem. Rev., 257, 1764.
- Leung KH, He HZ, Chan DSH, Fu WC, Leung CH, Ma DL.* (2013) An oligonucleotide-based switch-on luminescent probe for the detection of kanamycin in aqueous solution. Sensor. Actuat. B Chem., 177, 487.
- Yang H, Ma VPY, Chan DSH, Leung CH, Ma DL.* (2013) A cyclometallated iridium(III) complex as a c-myc G-quadruplex stabilizer and down-regulator of c-myc oncogene expression. Curr. Med. Chem., 20, 576.
- Ma DL,* Ma VPY, He HZ, Leung KH, Chan DSH, Leung CH. (2013) An overview of bioactive luminescent transition metal complexes for biomedical applications. Angew. Chem. Int. Ed., 52, 7666.
- Leung KH, He HZ, Ma VPY, Zhong HJ, Chan DSH, Zhou J, Mergny JL, Leung CH (Corresponding author),* Ma DL.* (2013) Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe. Chem. Commun., 49, 5630.
Front Cover - Chan DSH, Fu WC, Wang M, Liu LJ, Leung CH, Ma DL.* (2013) A highly selective and non-reaction based chemosensor for the detection of Hg2+ ions using a luminescent iridium(III) complex. Plos One, 8, e60114.
- Ma DL,* Zhong HJ, Fu WC, Chan DSH, Kwan HY, Fong WF, Chung LH, Wong CY, Leung CH. (2013) Phosphorescent imaging of living cells using a red-emitting iridium(III) complex. Plos One, 8, e55751.
- He HZ, Chan DSH, Leung CH (Corresponding author),* Ma DL.* (2013) G-quadruplexes for luminescent sensing and logic gates. Nucleic Acids Res., 41, 5345.
- Ma DL,* He HZ, Leung KH, Zhong HJ, Chan DSH, Leung CH. (2013) Label-free luminescent oligonucleotide-based probes. Chem. Soc. Rev .,42, 3427.
- Ma DL,* Chan DSH, Leung CH (Corresponding author).* (2013) Drug repositioning by structure-based virtual screening. Chem. Soc. Rev., 42, 2130.
- Leung CH (Corresponding author),* Chan DSH, Li YW, Fong WF, Ma DL.* (2013) Hit identification of IKKbeta natural product inhibitor. BMC Pharmacol Toxicol., 14, 3.
Editor’s pick - He HZ, Leung KH, Fu WC, Chan DSH, Leung CH, Ma DL.* (2012) Application of a DNA-based luminescence switch-on method for the detection of mercury(II) ions in water samples of Hong Kong. Environ. Res. Lett., 7, 044032.
- Leung KH, He HZ, Ma VPY, Yang H, Chan DSH, Leung CH (Corresponding author),* Ma DL.* (2012) A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase. RSC Adv., 3, 1656.
- Leung KH, Ma VPY, He HZ, Chan DSH, Leung CH, Ma DL.* (2012) A highly selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar strontium(II) ion in sea water. RSC Adv., 2, 8273.
- Ma DL,* Ma VPY, Chan DSH, Leung CH. (2012) Recent advances in luminescent heavy metal complexes for sensing. Coord. Chem. Rev., 256, 3087.
- Leung CH (Corresponding author),* Yang H, Ma VPY, Chan DSH, Zhong HJ, Lau WF, Li YW, Fong WF, Ma DL.* (2012) Inhibition of Janus kinase 2 by cyclometalated rhodium complexes. Med. Chem. Comm., 3, 696.
- Leung CH (Corresponding author),* Chan DSH, Ma VPY, Ma DL.* (2012) DNA-binding small molecules as inhibitors of transcription factors. Med. Res. Rev., 33, 823.
- Leung KH, He HZ, Ma VPY, Chan DSH, Leung CH (Corresponding author),* Ma DL.* (2012) A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione. Chem. Commun., 49, 771.
Front Cover - Ma DL,* Chan DSH, Ma VPY, Leung KH, Zhong HJ, Leung CH. (2012) Current advancements in Abeta luminescent probes and inhibitors of Abeta aggregation. Curr. Alzheimer Res., 9, 830.
- Yang H, Zhong HJ, Leung KH, Chan DSH, Ma VPY, Fu WC, Nanjunda R, Wilson WD, Ma DL,* Leung CH (Corresponding author).* (2012) Structure-based design of flavone derivatives as c-myc oncogene down-regulators. Eur. J. Pharm. Sci., 48, 130.
- Zhong HJ, Yang H, Chan DSH, Leung CH, Wang HM, Ma DL,*. (2012) A Metal-based inhibitor of NEDD8-activating enzyme. PLoS One, 7, e49574.
- He HZ, Leung KH, Yang H, Chan DSH, Leung CH, Zhou J, Bourdoncle A, Mergny JL, Ma DL.* (2012) Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe. Biosens. Bioelectron., 41, 871.
- Ma DL,* Chan DSH, Fu WC, He HZ, Yang H, Yan SC, Leung CH (Corresponding author).* (2012) Discovery of a natural product-like c-myc G-quadruplex DNA groove-binder by molecular docking. PLoS One, 7, e43278.
- Zhong HJ, Ma VPY, Cheng Z, Chan DSH, He HZ, Leung KH, Ma DL,* Leung CH (Corresponding author).* (2012) Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening. Biochimie, 94, 2457.
- Leung CH (Corresponding author),* Zhong HJ, Yang H, Cheng Z, Chan DSH, Ma VPY, Abagyan R, Wong CY, Ma DL.* (2012) A metal-based inhibitor of tumor-necrosis factor-alpha. Angew. Chem. Int. Ed., 51, 9010.
Frontispiece - Ye D, Shi Q, Leung CH, Kim SW, Park SY, Gullen EA, Jiang ZL, Zhu H, Morris-Natschke SL, Cheng YC, Lee KH. (2012) Antitumor agent 294. Novel E-ring-modified camptothecin-4b-anilino-4’-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents. Bioorg. Med. Chem., 20, 4489.
- He HZ, Chan DSH, Leung CH, Ma DL.* (2012) A highly selective G-quadruplex-based luminescent switch-on probe for the detection of gene deletion. Chem. Commun., 48, 9462.
Back cover - Ma DL,* Ma VPY, Chan DSH, Leung KH, Zhong HJ, Leung CH. (2012) In silico screening of quadruplex-binding ligands. Methods, 57, 106.
- Ma DL,* He HZ, Ma VPY, Chan DSH, Leung KH, Zhong HJ, Lau WF, Mergny JL, Leung CH. (2012) Label-free sensing of pH and silver nanoparticles using an “OR” logic gate. Anal. Chim. Acta., 733, 78.
- Ma DL,* Chan DSH, Yang H, He HZ, Leung CH (Corresponding author).* (2012) Luminescent G-quadruplex probes. Curr. Pharm. Design, 18, 2058.
- Leung CH (Corresponding author),* Chan DSH, He HZ, Cheng Z, Yang H, Ma DL.* (2012) Luminescent Detection of DNA-binding Proteins. Nucleic Acids Res., 40, 941.
- He HZ, Ma VPY, Leung KH, Chan DSH, Yang H, Cheng Z, Leung CH, Ma DL.* (2012) A label-free G-quadruplex-based switch-on fluorescence assay for the selective detection of ATP. Analyst, 137, 1538.
- Liu J, Sun RWY, Leung CH, Lok CN, Che CM. (2012) Inhibition of TNF-a stimulated nuclear factor-kappaB activation by cyclometalated platinum(II) complexes. Chem. Commun., 48, 230.
- Ma VPY, Leung KH, Chan DSH, Lam WC, Leung CH (Corresponding author),* Ma DL.* (2011) Recent development of c-myc G-quadruplex ligands. International Review of Biophysical Chemistry, 2, 120.
- Ma VPY, Lam WC, Ma DL,* Leung CH (Corresponding author).* (2011) Hit Identification of anthraquinone based molecules as c-myc G-quadruplex inducer/stabilizer via in silico structural similarity approach. International Review of Biophysical Chemistry, 2, 108.
- Ma DL,* Chan DSH, Leung CH (Corresponding author).* (2011) Molecular Docking for Virtual Screening of Natural Product Databases. Chem. Sci., 2, 1656.
- Zhu GY, Li YW, Tse AKW, Hau DKP, Leung CH, Yu ZL, Fong WF. (2011) 20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells. Eur. J. Pharmacol, 668, 88.
- Ma DL,* Kwan MHT, Chan DSH, Lee P, Yang H, Bai LP, Jiang ZH, Leung CH (Corresponding author).* (2011) Crystal violet as a fluorescent switch-on probe for i-motif: Label-free DNA-based logic gate. Analyst, 136, 2692.
- Ma DL,* Chan DSH, Lee P, Kwan MH, Leung CH (Corresponding author).* (2011) Molecular modeling of drug-DNA interactions: virtual screening to structure-based design. Biochimie, 93, 1252.
- Man BYW, Chan HM, Leung CH, Chan DSH, Bai LP, Jiang ZH, Li HW,* Ma DL.* (2011) Group 9 metal-based inhibitors of b-amyloid (1–40) fibrillation as potential therapeutic agents for Alzheimer’s disease. Chem. Sci. 2, 917.
- Ma DL,* Xu T, Chan DSH, Man BYW, Fong WF, Leung CH (Corresponding author).* (2011) A Highly Selective, Label-Free, Homogenous Luminescent Switch-On Probe for the Detection of Nanomolar Transcription Factor NF-kappaB. Nucleic Acids Res., 39, e67.
- Chan DSH, Yang H, Kwan MHT, Cheng Z, Bai LP, Jiang ZH, Wong CY, Leung CH (Corresponding author),* Ma DL.* (2011) Structure-based Optimization of FDA-Approved Drug Methylene Blue as a c-myc G-Quadruplex DNA Stabilizer. Biochimie, 93, 1055,
- Ma DL,* Chan DSH, Man BYW, Leung CH (Corresponding author).* (2011) Oligonucleotide-based luminescent detection of metal ions. Chem. Asian. J. 6, 986.
- Leung CH (Corresponding author),* Chan DSH, Kwan MHT, Cheng Z, Wong CY, Zhu GY, Fong WF, Ma DL.* (2011) Structure-Based Repurposing of FDA-Approved Drugs as TNF-α Inhibitors. Chem. Med. Chem., 6, 765.\
- Wang P, Leung CH (Co-first author), Ma DL, Yan SC, Chen QS, Che CM. (2011) Specific blocking of CREB/DNA binding by cyclometalated platinum(II) complexes. Angew. Chem. Int. Ed., 50, 2554.
- Leung CH (Corresponding author),* Chan DSH, Abagyan R, Lee SMY, Zhu GY, Fong WF, Ma DL.* (2011) A natural product-like inhibitor of NEDD8-activating enzyme. Chem. Commun., 47, 2511.
Front cover - Wang N, Feng Y, Xie TN, Su W, Zhu M, Chow O, Zhang Y, Ng KM, Leung CH, Tong Y. (2011) Chemical and biological analysis of active free and conjugated bile acids in animal bile using HPLC-ELSD and MTT methods. Exp. Ther. Med., 2, 125.
- Leung CH (Corresponding author),* Chan DSH, Man BYW, Wang CJ, Lam W, Cheng YC, Fong WF, Hsiao WLW, Ma DL.* (2011) Simple and convenient G-quadruplex-based turn-on fluorescence assay for 3’-5’exonuclease activity. Anal. Chem., 83, 463.
Front cover - Liu J, Leung CH, Chow AL, Sun RW, Yan SC, Che CM. (2011) Cyclometalated platinum(II) complexes as topoisomerase IIa poisons. Chem. Commun., 47, 719.
- Man BYW, Chan DSH, Ang SW, Yang F, Yang H, Wu P, Ho CM, Yan SC, Che CM, Leung CH (Corresponding author),* Ma DL.* (2010) A selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar silver(I) ion in aqueous solution. Chem. Commun., 46, 8534.
Front cover - Feng Y, Siu KY, Ye X, Wang N, Yuen MF, Leung CH, Tong Y, Kobayashi S. (2010) Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats. Chin. Med., 5, 33.
- Wang P, Leung CH, Ma DL, Lu W, Che CM. (2010) Organoplatinum(II) complexes with nucleobase motifs as human topoisomerase II catalytic inhibitors. Chem. Asian J., 5, 2271.
- Lee HM, Chan DSH, Yang F, Lam HY, Yan SC, Che CM, Ma DL,* Leung CH (Corresponding author).* (2010) Identification of natural product fonsecin as a stabilizing ligand of c-Myc G-quadruplex DNA by high-throughput virtual screening. Chem. Commun., 46, 4680.
Front cover - Wang P, Leung CH, Ma DL, Yan SC, Che CM. (2010) Structure-based design of platinum(II) complexes as c-Myc oncogene down-regulators and luminescent probes for G-quadruplex DNA. Chem. Eur. J., 16, 6900.
- Yan JJ, Chow ALF, Leung CH, Sun RWY, Ma DL, Che CM. (2010) Cyclometalated gold(III) complexes with N-heterocyclic carbene ligands as topoisomerase I poisons. Chem. Commun., 46, 3893.
- Chan DSH, Lee HM, Yang F, Che CM, Wong CCL, Abagyan R, Leung CH (Corresponding author),* Ma DL.* (2010) Structure-Based Discovery of Natural Product-Like TNF-alpha Inhibitors. Angew. Chem. Int. Ed., 49, 2860.
Frontispiece A hot paper chosen by the Editors for its importance in a rapidly evolving field of high current interest Highlighted by SciBX, Nature Publishing Group, 2010, 3(13) - Sun RW, Li CK, Ma DL, Yan JJ, Lok CN, Leung CH, Zhu N, Che CM. (2010) Stable anti-cancer gold(III) porphyrin complexes: effects of porphyrin structure. Chem. Eur. J., 16, 3097.
- Chan DSH, Lee HM, Che CM, Leung CH (Corresponding author),* Ma DL.* (2009) A selective oligonoucleotide-based luminescent switch-on probe for the detection of nanomolar mercury(II) ion in aqueous solution. Chem. Commun., 48, 747
- Leung CH (Corresponding author),* Lam W, Ma DL, Gullen EA, Cheng YC.* (2009) Butyrate mediates nucleotide-binding and oligomerisation domain (NOD) 2-dependent mucosal immune responses against peptidoglycan. Eur J Immunol 39, 3529.
- Wu P, Ma DL, Leung CH, Yan SC, Zhu N, Abagyan R, Che CM. (2009) Stabilization of G-quadruplex DNA with platinum(II) schiff-base complexes: Luminescent probe and down regulation of c-myc oncogene expression. Chem Eur J 15, 13008.
- Park SY, Leung CH, Cheng YC. (2008) ATP modulates poly(ADP-ribose) polymerase-1-facilitated topoisomerase I-linked DNA religation in the presence of camptothecin. Mol. Pharmacol, 73 (6), 1829-1837.
- Gao W, Chen APC, Leung CH, Gullen EA, Fürstner A, Shi Q, Wei L, Lee KH, Cheng YC. (2008) Structural analogs of tylophora alkaloids may not be functional analogs. Bioorganic Med. Chem. Lett., 18 (2), 704-709.
- Lam W, Leung CH, Bussom S, Cheng YC. (2007) The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine. Mol. Pharmacol. 72 (3), 536-544.
- Ying C, Li Y, Leung CH, Robek MD, Cheng YC. (2007) Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue. PNAS., 104 (20), 8526-8531.
- Fong WF, Wang C, Zhu GY, Leung CH, Yang MS, Cheung HY. (2007) Reversal of multidrug resistance in cancer cells by Rhizoma Alismatis extract. Phytomedicine, 14 (2-3), 160-165.
- Leung CH, Grill SP, Lam W, Gao W, Sun HD, Cheng YC. (2006) Eriocalyxin B inhibits nuclear factor-κB activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner. Mol. Pharmacol, 70 (6),1946-1955.
- Lam W, Park SY, Leung CH, Cheng YC. (2006) Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and β-L-2′,3′-dideoxy-2′,3′-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and β-D-arabinofuranosylcytosine). Mol. Pharmacol, 69 (5), 1607-1614.
- Cheng YC, Ying CX, Leung CH, Li Y. z(2005) New targets and inhibitors of HBV replication to combat drug resistance. J. CLIN. VIROL, 34, S147-S150.
- Leung CH, Grill SP, Lam W, Han QB, Sun HD, Cheng YC. (2005) Novel mechanism of inhibition of nuclear factor-κB DNA-binding activity by diterpenoids isolated from Isodon rubescens. Mol. Pharmacol., 68 (2), 286-297.
- Lam W, Chen C, Ruan S, Leung CH, Cheng YC. (2005) Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake. Mol. Pharmacol., 67 (2), 408-416.
- Zhuang WJ, Fong CC, Cao J, Ao L, Leung CH, Cheung HY, Xiao PG, Fong WF, Yang MS. (2004) Involvement of NF-κB and c-myc signaling pathways in the apoptosis of HL-60 cells induced by alkaloids of Tripterygium hypoglaucum (levl.) Hutch. Phytomedicine, 11 (4), 295-302
- Wu JYC, Fong WF, Zhang JX, Leung CH, Kwong HL, Yang MS, Li D, Cheung HY. (2003) Reversal of multidrug resistance in cancer cells by pyranocoumarins isolated from Radix Peucedani. Eur. J. Pharmacol., 473 (1), 9-17.
- Leung CH, Lam W, Zhuang WJ, Wang NS, Fong WF. (2001) PKCδ-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF. Biochem. Biophys. Res. Commun., 285 (2), 283-288.
- Fong WF, Leung CH, Lam W., Wong NS, Cheng SH. (2001) Epidermal growth factor induces Gadd45 (growth arrest and DNA damage inducible protein) expression in A431 cells. Biochim. Biophys. Acta, Gen. Subj., 1517 (2), 250-256
- Lam W, Leung CH, Chan HL, Fong WF. (2000) Toxicity and DNA binding of dextran-doxorubicin conjugates in multidrug-resistant KB-V1 cells: Optimization of dextran size. Anticancer Drugs, 11 (5), 377-384.